Peptides are gaining a great deal of attention in the scientific market today. These chemicals are naturally developed from amino acids in the body and can be used both as triggers and messengers– to create certain reactions within groups of tissue. Peptides can cause seemingly endless reactions within the body, depending on how they are triggered and which tissues they interact with.
It is believed that if peptides can be produced synthetically, they could have a strong pharmaceutical use. Testing on animals, tissue samples and other means are currently being worked by the scientist— to determine how these peptides could be used in pharmaceutical applications in the future.
Naturally, peptides have a very short time period where they are viable for use by bodily tissues. They are designed to break down quickly once they enter the bloodstream so that an animal’s body can harvest the various amino acids that make up these chains and use them for a variety of reactions as necessary.
This limits the ability to harvest these peptides and apply them in a research setting because long peptides that break down very quickly cannot be stored or given any type of shelf life. A variety of alterations to the build of common peptides have been suggested, as a means of addressing this issue.
Storing and Using Peptides in Research
Even the best peptides still have limitations that should be considered when purchasing large quantities of chemicals in a research project.
- Proper storage and transport of a peptide is essential to maintaining its composition. Top peptide suppliers typically ship peptides in lyophilized form— with the intention of having them stored in hydroscopic form, to maintain the structure of the chemical for as long as possible. To further ensure the quality of the peptides, a desiccator should be used to ensure that they are kept in an environment that is dry and free from any particles that could alter the quality or structure of the chemical.
- Peptides should remain frozen until they are to be used to extend the shelf life of the product. The use of a frost free freezer is not commonly recommended for storing peptides as these machines greatly alter the temperature and moisture levels within the storage facility that can have a negative impact on the delicate peptides which are being stored here.
- If you are working with a new peptide supplier, ask what precautions are taken to ensure stability of the product during shipping. Short term changes in temperatures or moisture levels can have a disastrous effect on the stability or the safety of peptides that will be used in research settings. The best peptide suppliers have taken these concerns into account and will use temperature controlled settings in every environment where a peptide is produced, packaged and stored– to ensure maximum stability and quality of product for the research facilities that will receive these shipments.
- Peptides can be kept in cold storage for up to two years if they are kept sealed, dry and at around -20 degrees Celsius. Once it comes time to use these peptides in applications to animal test subjects, they will need to be slowly brought to room temperature and reconstituted. The specific methodology used for this process will vary, based on the methods that were used to create the original peptide. Instructions for reconstituting, including the liquids intended to be used for this purpose, should be outlined in the packaging of the peptide that was received with the initial purchase.
Those that are planning long term research should only measure out the amount of peptide they require for a given application, then quickly reseal the container and return it to the freezer for safe keeping. This will help to ensure consistent results in future applications.
Selecting a Supply Company
The best peptides for use in a research setting must be carefully prepared in order to ensure that they will provide uniform results and minimize negative reactions from the animals that are being used to test these reactions.
- Bulk peptides are typically purchased by researchers to ensure they will have enough supplies to run multiple trials of an experiment. It is not uncommon for experimentation to require the application of a peptide one or more times a day for a month or more in animal test subjects, which will require a great deal of supplies on hand to ensure that the experiment can be continued on a planned schedule.
- When they are produced properly, buying peptides in bulk can ensure consistency that will help to narrow down the types of reactions that peptides can cause when administered to animals. This is particularly helpful as researchers work to better understand the effects of peptides that have been altered to better suit the future needs of the pharmaceutical industry. This includes peptides that have had a preservative agent added to the formula or those whose bonds have been shortened or otherwise altered to increase their half-life—both on the shelf and in the animal’s bloodstream after application.
- In order to ensure the highest quality product for peptides are available for research, restrict your use to peptides that were produced in the United States. These peptides were created using consistent methods and are designed for research that is being done through United States pharmaceutical industries. This means that all peptides have been set to ensure the highest possible level of safety for animal test subjects and are created and stored in a way that ensures they will be sterile when applied to a research setting.
Maxim takes great care to ensure that all peptides they produce and sell are research-grade quality. This includes creating a bulk sized batch that is high enough quality to run multiple trials without the risk that the peptide will break down prematurely and begin to produce alternate results than those that are predicted.
This also means that all peptides produced and sold from this manufacturer were created in a sterile environment and designed with the intention of being used on animal test subjects, further ensuring that there will be no unexpected side effects or risks that could jeopardize the integrity of a research project.
Given the vast amount of reactions that have been seen between peptides and animal tissues both from natural peptides that are produced by animal’s body and those that have been applied to animal tissue via injection or other means, there is much variety in the peptides that might be appropriate for a research setting.
Scientists will frequently purchase a variety of peptides that have a similar function and compare their reactions against each other as a means of better understanding how these peptides react against bodily tissues in animals, particularly when they are synthetically made or applied externally.