GHRP-2 is a secretagogue whose chemical makeup enables it to promote the natural secretion of growth hormone amongst animal test subjects, per scientific research. At the same time, the peptide can stimulate the pituitary gland, the pea-sized gland found in the brain that is regarded as the heart of the endocrine system.
How GHRP-2 Works
GHRP-2’s main function as determined by scientific research conducted on animal test subjects is centered on building up muscle mass and stimulating hunger.
The peptide can accomplish both of these elements because it stimulates the inner workings of the pituitary gland, which causes an increase in the synthesis of proteins in animal test subjects. It can achieve this because it can prevent somatostatin; a peptide hormone that controls the endocrine system and influences cell propagation and neurotransmission via interaction with G protein-coupled receptors. Additionally, scientific studies have found that GHRP-2 can raise the levels of calcium ion influx, which can promote more growth production in animal test subjects.
GHRP-2 also stimulates the production of ghrelin; a self-regulating peptide produced chiefly by the stomach as a means to stimulate hunger in animal test subjects. This enhanced ghrelin production allows for an increased desire amongst animal test subjects to eat. Furthermore, GHRP-2 also promotes eleveated levels of IGF-1; a protein produced by the liver that plays a large role in muscle and tissue repair and growth.
Additionally, GHRP-2 has been connected to an increase in hypothalamus functionality. This boost, like the increase in ghrelin production levels, also helps to increase appetite in animal test subjects.
GHRP-2 does have a markedly low half-life, ranging from 15 minutes to an hour once it has been given to an animal test subject. This means that the peptide’s effectiveness is very limited in animal test subjects unless it is given to them frequently.
GHRP – 2 Benefits
According to scientific research conducted on animal test subjects, GHRP-2 has been determined to contain host of theoretical benefits.
The primary theoretical benefit based on animal test subject research is the promotion of muscular repair and growth. This is due to the peptide’s capability to induce a higher level of protein secretion relating to growth and repair.
The secondary theoretical benefit is an increased appetite. Because GHRP-2 promotes the production of ghrelin, animal test subjects experienced an increased tendency to feel hungry. This increase is coupled with the peptide’s ability to break down fat mass. GHRP-2’s mechanics enable animal test subjects to burn off adispose tissue at a faster rate, leading to the subject’s ability to break down excess fat cells more efficiently. This in turn allows for the fat of animal test subjects to be diminished over a shorter time frame, as well as an increased maintenance of incoming fat cells.
A third theoretical benefit of the peptide it its possible capability to improve the anti-inflammatory actions in an animal test subject. Scientific research has determined that GHRP-2 can potentially lessen instances of negative reaction that an animal test subject’s body may have to damaged cells, irritants, or other assorted pathogens. These reactions include swelling, pain, decreased functionality, and more.
Other theoretical benefits concerning GHRP-2 include:
- Enhanced defense of the liver
- Improved skin elasticity
- Improved bone density
- Lowering of cholesterol levels
GHRP-2’s Side Effects
While scientific research on GHRP-2 conducted via animal test subjects have resulted in several theoretical benefits, several negative side effects have been noted as well. The side effects that have been linked to GHRP-2 include:
- Tightness and/or carpel tunnel-type symptoms.
- Tingling and numbness in the extremities.
- A decrease in insulin sensitivity.
- An increase in water retention.
- Increased instances of fatigue.
Notes about Clinical Studies and GHRP-2
While both positive theoretical benefits and negative side effects have been linked to GHRP-2 in conjunction with scientific research on animal test subjects, it should be noted that these types of test results have not been determined to officially be considered consistent. The reason for this chiefly due to the fact that the inner workings of the pituitary gland have a tendency to respond differently to the peptide from one animal test subject to another.
This, among other reasons, is why it also be noted that GHRP-2 is still in being researched scientifically on animal test subjects. Because of this, it is considered to be a lyophilized peptide and should only be used for clinical research. Its processes, operations, and mechanics should only be viewed within the parameters of a strictly and thoroughly controlled environment, such as a scientific research facility or a laboratory.