Tamoxifen Citrate is largely considered to be an antagonist peptide of the estrogen receptors found in breast tissue. It is sometimes referred to as Nolvadex, Valodex, or Istubal.
Mechanics of Tamoxifen Citrate
According to scientific research that has been conducted on animal test subjects, the precise mechanisms relating to how Tamoxifen Citrate works is not completely known. However, it is generally theorized that the peptide works by being an antagonist of the estrogen receptors found in breast tissue. Specifically, its antagonistic properties are linked to its active metabolite known as hydroxytamoxifen.
What this means, is that the peptide is such that it does not induce a biological response once it is bound to a specific receptor. Instead, it functions to block or inhibit the typical agonist-mediated response that would normally tie in with certain cellular functions, such as its properties of secretion. As such, scientific study based on animal test subjects have determined that Tamoxifen Citrate binds with estrogen receptors found in breast tissue and inhibits the production of endocrine-related secretions by the cells located within the tissue. This then inhibits the production of estrogen that is produced by breast tissue cells.
Additionally, it has been determined that Tamoxifen Citrate is cytotastic, meaning that the peptide does not cause cellular death as a part of its functionality.
Theoretical Benefits of Tamoxifen Citrate
Scientific research that has been conducted on animal test subjects relating to Tamoxifen Citrate has determined that the peptide could provide a host of theoretical benefits.
The primary focus of this research is related to Tamoxifen Citrade’s relation to the treatment of breast cancer in pre-and post-menopausal animal test subjects. It has been determined that the proliferation of some breast cancer cells is promoted by activated estrogen receptors in the breast tissue. This has also been determined to be a root cause of metastatic breast cancer, or breast cancer that has spread to other parts of the body. Scientific study conducted on animal test subjects has determined that the peptide’s capability to inhibit estrogen receptors in breast tissue cells can slow down the proliferation of cancerous cell production. This in turn can be utilized to curb the growth and spread of breast cancer within animal test subjects.
Other theoretical benefits that have been linked to the functionality of Tamoxifen Citrate include:
- Treatment of McCune-Albright syndrome – This condition is a genetic disorder that is caused by endocrine hyperfunction. The syndrome is caused by an excess production of estrogen and is marked by an imbalance of skin pigmentation throughout the body, bone deformity in the skull and extremities, and the onslaught of puberty at an unusually early time (a condition that is sometimes referred to as precocious puberty). Scientific research conducted on animal test subjects has determined that the peptide’s ability to inhibit the production of estrogen may cause a regulatory effect on such secretions, which could in turn stem the proliferation of this syndrome.
- Treatment of Gynecomastia – This condition is marked by the benign enlargement of breast tissue in male animal test subjects. It is theorized that the peptide’s ability to block the production of estrogen could inhibit the triggering of this type of enlargement.
- Treatment of Riedel’s thyroiditis – This chronic form of autoimmune thyroiditis is caused by a dense fibrosis that invades the thyroid and causes symptoms related to tracheal compression. It is theorized that the peptide’s inhibiting qualities could result prohibit the release of secretions related to the cause of the fibrosis.
Potential Negative Side Effects of Tamoxifen Citrate
it should be noted that there have also been a few potential negative side effects that have been associated with the Tamoxifen Citrate. Some of these side effects linked to the peptide include:
- Weight gain
- Absence of menstrual periods
- Vaginal discharge
- Fluid retention
- Pane in bones
- Conditions related to blood clots, including pulmonary embolism or deep vein thrombosis
For Scientific Use Only
While there have been several scientific studies conducted on animal test subjects in order to determine Tamoxifen Citrate’s range of mechanics, theoretical benefits, and negative side effects, it should be noted that all findings that are associated with the peptide are still considered to be the product of current laboratory research. Because Tamoxifen Citrate is currently in the research phase, any study or usage liked to the mechanics, operations, benefits, and side effects of the peptide should exclusively be contained to the restrictions of a strictly controlled environment such as a laboratory or medical research facility.